In this remarkable book, Charles P. Pierce intertwines two dramatic stories-the scientific race to discover the causes of Alzheimer's and the moving experiences of the Pierce family as they struggle with the disease.

More than four million Americans develop Alzheimer's every year, just as Charles Pierce's father did-horrifically and genetically-and in Hard to Forget, Pierce takes us deep into the country of this disease, to explore how it affects both the body and a family. When his father is diagnosed with Alzheimer's, the author goes on a quest to discover everything he can about the disease. He discusses here Dr. Alois Alzheimer's work early in the twentieth century, then shows how Watson and Crick's announcement of the double-helix structure of DNA opened up the field of Alzheimer's research and led to discoveries by the "genome cowboys"-Dr. Allen Roses, Dr. Peter Hyslop, and others-of the genetic components of the disease. At the heart of this book, too, is the powerful, emotional story of how the Pierce family coped with Alzheimer's and with the threat that the author-and his children-might also inherit it.

Elegant and richly informative, Hard to Forget is a unique and provocative book.

Customer Reviews:

Avg. Customer Rating: 4.5 / 5.0

Much more than an Alzheimer's story...:

I had to search hard to find this book, because other "Charles Pierces" kept coming up online and it was hidden in "aging" or "disease, listed alphabetically" in the bookstores, but I recommend you persevere -- it was worth it. Somehow the author manages to combine a poignant memoir, exploring the way we're taught in our families of origin to deal (or not deal, in the case of the Pierces) with serious issues, with a highly readable account of what doctors know and are racing to find out about this cruel... more info

Informative, quick read:

Fortunately, my family has no history of Alzheimer's disease. My only experience with the disease came from my next door neighbor. An elderly couple moved into the house next store to my family home when I was only 3 years old. The couple became my third set of grandparents. The husband, Howard, died about three years later. His wife began to suffer from Alzheimer's shortly after his death. I remember being very confused when she asked me to fetch her sweater that was upstairs on the sewing machine, when... more info

Honest story-telling and solid reporting:

As an Alzheimer's family member, I read "Hard to Forget" with great interest. When my mother was diagnosed 13 years ago, my family went through stages of initial denial and then finally accepting the diagnosis and then coping as best we could...a similar story to the Pierce family - and to so many other families. The difference is that my mother was not an "early onset" patient. Hers is probably not the "familial" Alzheimer's Disease. And the terror is not as great for my sister and I as it is for Charles... more info

To The Scientist:

I just finished Charles Pierce's book and must say that I was very moved by it. In reading your reviews I was struck by the comments by the research scientist who pointed out all the errors in Mr. Pierce's telling. Perfect illustration of his point, I think. We readers aren't quite as concerned with the exact dates as we are with the the evolution of the research as a whole. Can't you all just get along?

Similar Products: